ROMA (ITALPRESS) – The third episode of Science Calling, Neurosciences: travel in the “Medicine cerebral”, explores one of the most complex fields and in deep transformation of contemporary research: that of neurosciences. At the centre of the episode there is the evolution of knowledge about the functioning of the brain and neurological pathologies, observed through the contribution of clinical and translational research. The episode, available on Spotify, Apple Podcast and Amazon Music, is made with the non-conditional contribution of AbbVie and Argenx Italy and is part of the publishing project Science Calling, articulated in eight episodes and led by Myrta Merlino, produced and post-produced by Edulia, by Sapere Treccani. From here begins the comparison between clinical skills and translational research, entrusted to the dialogue between Myrta Merlino and two reference specialists in the neurological landscape: Angelo Antonini, Professor of Neurology at the Department of Neuroscience of the University of Padua, and researcher of international importance in the study of Parkinson and movement disorders, and Yuri Falzone, neurologist at the IRCS Hospital San Raffaele in Milan, engaged in the study of rare neuromuscular and neuroimmunological diseases. Through their voices, the episode explores an area where molecular biology and technological innovation directly affect understanding, diagnosis and therapeutic strategies of nervous system diseases. It is in this context that, as Myrta Merlin observed in the course of the episode, “the neurosciences offer a key to understanding ourselves and interpreting the changing world, overcoming the historical division between neurology and psychiatry and building a unified vision of brain medicine”. The conversation traces the evolution of neurology, from clinical-descriptive discipline to molecular and network science, able to investigate the biological mechanisms that precede and accompany the manifestation of symptoms. Research emerges as an increasingly fine reading of processes: from the accumulation of proteins badly folded to neuroinflammation, from the role of mitochondria and lysosomes to the understanding of neural networks that regulate motor, cognitive and emotional functions. Large space is dedicated to Parkinson’s disease, observed beyond the motor dimension. The episode focuses on the importance of non-motor symptoms, especially sleep disorders in advanced stages, which affect the quality of life and balance between day and night. Next to Parkinson, the episode deepens two rare neurological pathologies of autoimmune origin: mystenia gravis and demyelinative chronic inflammatory polyneuropatia (CIDP). In the story emerges the complexity of conditions characterized by variable clinical frameworks and often articulated diagnostic paths, which require specialist skills and a highly personalized approach. Research in this area is opening up new therapeutic perspectives, with targeted treatments able to selectively modulate the immune response and make management more sustainable in the long term, even on the organizational and welfare level. In closing, the episode expands its gaze from the treatment of individual pathologies to the protection of brain health throughout the life span. The brain is returned as an individual and collective resource, a capital to protect through early diagnosis, prevention, research and policies capable of integrating health, environment, education and social services. A path that transforms scientific knowledge into shared awareness and places neurosciences at the center of the health and social challenges of the present.
– photos Esperia Advocacy – (ITALPRESS).
